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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KDM5B
All Species:
20
Human Site:
T1133
Identified Species:
44
UniProt:
Q9UGL1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UGL1
NP_006609.3
1544
175645
T1133
S
D
L
E
R
A
L
T
E
S
K
E
T
A
S
Chimpanzee
Pan troglodytes
Q5XUN4
1535
173724
T1117
L
G
L
Y
Q
C
D
T
E
L
L
G
L
S
A
Rhesus Macaque
Macaca mulatta
XP_001090508
1411
159177
I1019
I
P
V
H
L
P
N
I
Q
A
L
K
E
A
L
Dog
Lupus familis
XP_537122
1727
195532
S1316
S
D
L
E
R
A
L
S
E
S
K
E
T
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q80Y84
1544
175537
M1133
S
D
L
E
R
A
L
M
E
S
K
E
T
A
A
Rat
Rattus norvegicus
NP_001100647
1544
175257
T1133
S
D
L
E
R
A
L
T
E
S
K
E
T
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508780
1538
174757
T1127
S
D
L
E
R
A
L
T
E
S
K
E
T
A
S
Chicken
Gallus gallus
Q5F3R2
1522
173443
S1108
S
D
L
E
R
A
L
S
E
S
K
D
T
A
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6IQX0
1503
171080
K1108
G
D
C
V
S
S
G
K
K
K
F
V
K
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VMJ7
1838
203974
K1268
A
E
I
V
A
S
F
K
H
A
E
E
Q
E
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23541
1477
170773
E1083
I
T
L
S
K
A
A
E
I
S
K
A
F
E
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.5
46.3
84.7
N.A.
94.2
93.9
N.A.
89.9
82.7
N.A.
63.3
N.A.
35.2
N.A.
29.2
N.A.
Protein Similarity:
100
64.5
61.3
86.7
N.A.
96.6
96.5
N.A.
94.7
90.4
N.A.
76.4
N.A.
50.5
N.A.
49
N.A.
P-Site Identity:
100
20
6.6
93.3
N.A.
86.6
100
N.A.
100
86.6
N.A.
6.6
N.A.
6.6
N.A.
26.6
N.A.
P-Site Similarity:
100
40
33.3
100
N.A.
93.3
100
N.A.
100
100
N.A.
20
N.A.
46.6
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
64
10
0
0
19
0
10
0
64
19
% A
% Cys:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
64
0
0
0
0
10
0
0
0
0
10
0
0
10
% D
% Glu:
0
10
0
55
0
0
0
10
64
0
10
55
10
19
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
10
0
10
0
0
% F
% Gly:
10
10
0
0
0
0
10
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
19
0
10
0
0
0
0
10
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
19
10
10
64
10
10
0
0
% K
% Leu:
10
0
73
0
10
0
55
0
0
10
19
0
10
10
19
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
10
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
55
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
55
0
0
10
10
19
0
19
0
64
0
0
0
10
46
% S
% Thr:
0
10
0
0
0
0
0
37
0
0
0
0
55
0
10
% T
% Val:
0
0
10
19
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _